Macbeth ends with the death of the tyrant at Macduff's hands and with Malcolm, son of Duncan, hailed as King of Scotland. Before that, Lady Macbeth dies.
In Act V, scene 1, Lady Macbeth walks in her sleep, rubs her hands, and murmurs about blood. In scene 5, as Malcolm's army approaches Dunsinane, Seyton announces to Macbeth that the queen is dead. He responds with the speech about tomorrow. Soon after, a Messenger swears that Birnam Wood is moving, and Macbeth begins to doubt the words of the witches.
In scene 7, Macbeth kills young Siward, who confronts him, and then fights Macduff. He says that no man born of woman can end him, and Macduff answers that he was torn by force from his mother's womb before his time. Macbeth hesitates but refuses to surrender: "I will not yield!" The two exit fighting.
Macduff returns with Macbeth's head and greets Malcolm as king. Malcolm gives the barons the title of Earls, promises to recall the exiles, and invites everyone to the coronation at Scone. In his speech, he mentions the queen in passing: he says that, "as is believed," she took her own life.